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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASS4 All Species: 13.94
Human Site: Y113 Identified Species: 30.67
UniProt: Q9NQ75 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ75 NP_001157588.1 786 87144 Y113 P P T P G P V Y E Q M R S W A
Chimpanzee Pan troglodytes XP_001169779 786 87081 Y113 P P T P G P V Y E Q M R S W A
Rhesus Macaque Macaca mulatta XP_001090515 786 86837 Y113 P P T P G P V Y E H M R S W V
Dog Lupus familis XP_534461 746 82524 R97 Q A L F T I P R P A R A S L P
Cat Felis silvestris
Mouse Mus musculus Q08EC4 804 88602 Y113 P P P Q G P V Y E P M R S W V
Rat Rattus norvegicus Q63767 968 104244 K220 Y L V P T P S K T Q Q G L Y Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509857 821 90320 V117 A G V Y E K M V G W V K K P S
Chicken Gallus gallus XP_417499 814 90427 K106 A S S S T Y E K M E G W V T S
Frog Xenopus laevis NP_001084484 853 95724 Y104 K I T N L P T Y E Q M D S V Y
Zebra Danio Brachydanio rerio XP_001341038 774 86396 L110 P A N R L A P L S P A E A E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782316 831 91548 D109 G L S S S M D D Y D I P P V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 93.6 64.2 N.A. 61 22.3 N.A. 51.4 43.4 38.5 29 N.A. N.A. N.A. N.A. 23.8
Protein Similarity: 100 98.8 96 72.3 N.A. 71.5 38 N.A. 66.8 60.5 55.6 45.2 N.A. N.A. N.A. N.A. 39.7
P-Site Identity: 100 100 86.6 6.6 N.A. 73.3 20 N.A. 0 0 46.6 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 86.6 6.6 N.A. 73.3 26.6 N.A. 26.6 20 46.6 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 19 0 0 0 10 0 0 0 10 10 10 10 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 10 0 10 0 10 0 0 0 % D
% Glu: 0 0 0 0 10 0 10 0 46 10 0 10 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 37 0 0 0 10 0 10 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 0 0 0 0 10 0 0 0 0 % I
% Lys: 10 0 0 0 0 10 0 19 0 0 0 10 10 0 0 % K
% Leu: 0 19 10 0 19 0 0 10 0 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 10 10 0 10 0 46 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 46 37 10 37 0 55 19 0 10 19 0 10 10 10 10 % P
% Gln: 10 0 0 10 0 0 0 0 0 37 10 0 0 0 19 % Q
% Arg: 0 0 0 10 0 0 0 10 0 0 10 37 0 0 10 % R
% Ser: 0 10 19 19 10 0 10 0 10 0 0 0 55 0 19 % S
% Thr: 0 0 37 0 28 0 10 0 10 0 0 0 0 10 0 % T
% Val: 0 0 19 0 0 0 37 10 0 0 10 0 10 19 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 10 0 37 0 % W
% Tyr: 10 0 0 10 0 10 0 46 10 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _